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Human CMKLR1 Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1657
Background
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derivedmolecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such asSKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immuneresponses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production inmacrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis andadipocyte metabolism.
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
CMKLR1
Synonyms
CMKLR1; chemokine-like receptor 1; chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; orphan G-protein coupled receptor, Dez; DEZ; ChemR23; CHEMERINR; MGC126105; MGC126106;
GeneID
MIM
UniProt ID
Q99788
Chromosome Location
12q24.1
Pathway
GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; signal transducer activity;

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