Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

Human CHRM3/Galpha15 Stable Cell Line-Chem-1

See other products for CHRM3
Cat.No.
CSC-RG0597
Background
The muscarinic acetylcholine receptor (mAChR) family consists of five GPCRs that mediate some of the neurotransmission functions of acetylcholine in the CNS and the periphery. The M1, M3 and M5 receptors couple to Gq to mobilize intracellular calcium, whereas the M2 and M4 receptors couple to Gi/o to inhibit cAMP production. M3 is expressed prominently in smooth muscle, and plays a primary role in mediating mAChR agonist-induced contractility. Mice lacking M3 have dilated pupils, which indicates a role for M3 in regulating tone of the pupillary sphincter muscle. In addition, M3 plays a role in feeding, as indicated by the lean and hypophagic phenotype of M3-null mice.
Growth Properties
Adherent
Host Cell
Chem-1
Ship
Dry ice
Gene Information
Official Symbol
CHRM3
Synonyms
CHRM3; cholinergic receptor, muscarinic 3; muscarinic acetylcholine receptor M3; acetylcholine receptor; muscarinic 3; m3 muscarinic receptor; acetylcholine receptor, muscarinic 3; HM3; EGBRS;
Gene ID
MIM
UniProt ID
P20309
Chromosome Location
1q41-q44
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cholinergic synapse, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
G-protein coupled acetylcholine receptor activity; G-protein coupled receptor activity; acetylcholine binding; drug binding; phosphatidylinositol phospholipase C activity; receptor activity; signal transducer activity;

Quick Inquiry

Please input "biogene" as verification code.

CHRM3 Related Products

Transfected Stable Cell Lines

By Gene symbol(7)
+Expand
By Species(7)
+Expand

Premade Virus Particles

By Gene symbol(1)
+Expand
By Species(1)
+Expand

Clones

By Gene symbol(10)
+Expand
By Species(10)
+Expand
By MicroRNA Accession No.(2)
+Expand

Contact Us

USA

Europe

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER