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Human CCR6/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1441
Background
CCR6 is a receptor for macrophage inflammatory protein (MIP)-3alpha (CCL20). It is expressed in immature dendritic cells as well as in B lymphocytes and memory T cells. In gene-targeted mice lacking CCR6, myeloid dendritic cells are either absent or underrepresented in the subepithelial dome compared with wild-type mice. CCR6 and its ligands contribute to the normal homeostatic regulation of extrathymic T cell development in the intestine.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CCR6
Synonyms
CCR6; chemokine (C-C motif) receptor 6; STRL22; C-C chemokine receptor type 6; BN 1; CD196; CKR L3; CMKBR6; DCR2; DRY 6; GPR CY4; GPR29; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; BN-1; DRY6; CCR-6; CKRL3; CKR-L3; GPRCY4; CC-CKR-6; C-C CKR-6;
Gene ID
MIM
UniProt ID
P51684
Chromosome Location
6q27
Pathway
Beta defensins, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;

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