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Human CCR6/Galpha15 Stable Cell Line-Chem-1

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Cat.No.
CSC-RG0633
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Growth Properties
Adherent
Host Cell
Chem-1
Ship
Dry ice
Gene Information
Official Symbol
CCR6
Synonyms
CCR6; chemokine (C-C motif) receptor 6; STRL22; C-C chemokine receptor type 6; BN 1; CD196; CKR L3; CMKBR6; DCR2; DRY 6; GPR CY4; GPR29; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; BN-1; DRY6; CCR-6; CKRL3; CKR-L3; GPRCY4; CC-CKR-6; C-C CKR-6;
Gene ID
MIM
UniProt ID
P51684
Chromosome Location
6q27
Pathway
Beta defensins, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;

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