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Human CCR10/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0490
Background
CCR10 (also known as GPR2) is selectively expressed by IgAsecreting cells including circulating IgA+ plasmablasts, as well as almost all IgA+ plasma cells in the salivary gland, small intestine, large intestine, appendix and tonsils. It is a receptor for CCL27/CTACK and CCL28/MEC. Expression of CCL27 in skin may play an important role in facilitating memory T cells that express CCR10
to enter into cutaneous sites during inflammation and in determining the metastatic destination of malignant melanoma.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CCR10
Synonyms
CCR10; chemokine (C-C motif) receptor 10; G protein coupled receptor 2 , GPR2; C-C chemokine receptor type 10; CCR-10; CC-CKR-10; C-C CKR-10; CC chemokine receptor 10; G protein-coupled receptor 2; G-protein coupled receptor 2; GPR2;
Gene ID
MIM
UniProt ID
P46092
Chromosome Location
17q21.1-q21.3
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;

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