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Human CCR10-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0198
Background
CCR10 (also known as GPR2) is selectively expressed by IgAsecreting cells including circulating IgA+ plasmablasts, as well as almost all IgA+ plasma cells in the salivary gland, small intestine, large intestine, appendix and tonsils. It is a receptor for CCL27/CTACK and CCL28/MEC. Expression of CCL27 in skin may play an important role in facilitating memory T cells that express CCR10 to enter into cutaneous sites during inflammation and in determining the metastatic destination of malignant melanoma.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
CCR10
Synonyms
CCR10; chemokine (C-C motif) receptor 10; G protein coupled receptor 2 , GPR2; C-C chemokine receptor type 10; CCR-10; CC-CKR-10; C-C CKR-10; CC chemokine receptor 10; G protein-coupled receptor 2; G-protein coupled receptor 2; GPR2;
Gene ID
MIM
UniProt ID
P46092
Chromosome Location
17q21.1-q21.3
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;

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