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Human CCR1/beta-Arrestin Stable Cell Line-U2OS

Cat.No.
CSC-RG1435
Abbr
U2OS-HuCCR1/beta-Arrestin
Alias
CCR1,CMKBR1,SCYAR1,CD191,CKR 1,MIP1aR,CCR-1,CC-CKR-1,CKR1,CKR-1,HM145,CMKBR1,SCYAR1
Growth Properties
Adherent
Host Cell
U2OS
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
CCR1 is a CC chemokine receptor with high affinity for RANTES. It is demonstrated that targeted disruption of the CCR1 receptor is associated with protection from pulmonary inflammation secondary to acute pancreatitis in the mouse. The protection from lung injury is associated with decreased levels of TNFalpha in a temporal sequence indicating that the activation of the CCR1 receptor is an early event in the systemic inflammatory response syndrome.

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