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Human CCKBR-FLAG Stable Cell Line-HEK293T

See other products for CCKBR
Cat.No.
CSC-RG0427
Background
Cholecystokinin B receptor (CCKBR/CCK2R) is a 447-amino acid 7 transmembrane protein. The cholecystokinin (CCK) family of peptides and their receptors are widely distributed throughout the central nervous system and gastrointestinal tract. CCKBR is a type B (gastrin) receptor that has high affinity for both sulfated and nonsulfated CCK analogs found principally in the CNS and select
areas of the gastrointestinal tract. Type B receptors regulate anxiety, arousal, neuroleptic activity and opiate-induced analgesia. Outside of the CNS they regulate gastric acid secretion and may play a role in gastrointestinal motility and growth of normal and neoplastic gastrointestinal tissue. Northern hybridization shows CCKBR expressed in the stomach, pancreas, brain and gallbladder.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
CCKBR
Synonyms
CCKBR; cholecystokinin B receptor; gastrin/cholecystokinin type B receptor; CCK-BR; CCK2-R; CCK2 receptor; CCK-B receptor; gastrin receptor; cholecystokinin-2 receptor; GASR; CCK-B; CCK2R;
Gene ID
MIM
UniProt ID
P32239
Chromosome Location
11p15.4
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
1-phosphatidylinositol-3-kinase regulator activity; G-protein coupled receptor activity; cholecystokinin receptor activity; gastrin receptor activity; phosphatidylinositol phospholipase C activity; receptor activity; signal transducer activity; type B gastrin/cholecystokinin receptor binding;
Related Products
Cat#
Product Name
Host Cell
Gene Symbol
Species
Price
CSC-SC002608
HEK293 ,CHO, etc.
CCKBR
Human
CSC-DC002608
HEK293 ,Hela, etc.
CCKBR
Human
CSC-RG0821
CHO-K1
CCKBR
Human
Cat#
Product Name
Titer
Product Size
Species
Price
AD03218Z
>1x 10^9 vp/ml
1 x 0.2 ml
Human

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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