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Human CALCR Stable Cell Line-CHO-K1/Gα15

Cat.No.
CSC-RG1654
Host Cell
CHO-K1/Gα15
Shipping
Dry Ice
Source
CHO-K1/Gα15
Species
Human
Subgroup
Human
Background
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Gene Information
Gene Symbol
CALCR
Synonyms
CALCR; calcitonin receptor; CTR; CRT; CT-R; CTR1;
Gene ID
UniProt ID
P30988
mRNA Refseq
BC069611
Chromosome Location
7q21.3
Function
calcitonin binding; NOT calcitonin binding; calcitonin binding; calcitonin receptor activity; calcitonin receptor activity; protein binding; protein transporter activity; receptor activity; receptor activity; signal transducer activity;
Pathway
Calcitonin-like ligand receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
MIM

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