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Human C5AR1/beta-Arrestin Stable Cell Line-CHO

Cat.No.
CSC-RG1422
Abbr
CHO-HuC5AR1/beta-Arrestin
Alias
C5AR1,C5A,C5AR,CD88,C5a-R,C5R1
Growth Properties
Adherent
Host Cell
CHO-K1
Morphology
Epithelial-like
Shipping
Dry ice
Species
Human
Background
C5a receptor (C5a anaphylatoxin chemotactic receptor, or CD88 antigen, C5R1) is a receptor for chemotactic and inflammatory peptide anaphylatoxin C5a. C5a is a classic, potent inflammatory mediator, and the C5R1 receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. C5a receptor antagonists, such as AcPhe[Orn-Pro-D-cyclohexylalanine-Trp-Arg], show therapeutic effects in various inflammatory disease models. C5a receptor may also be involved in neurodegeneration and Alzheimer"s disease.

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