Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

Human C3AR1/Apoaequorin Stable Cell Line-CHO

See other products for C3AR1
Cat.No.
CSC-RG1245
Background
C3a, along with C4a and C5a, is a 77 amino acid anaphylotoxin generated by proteolytic cleavage during activation of the complement pathway. The anaphylotoxins strongly promote inflammation by recruiting leukocytes, particularly basophils, eosinophils, neutrophils and monocyte. The proinflammatory properties of C3a are mediated by interaction between the peptide and a 7-TM G-protein coupled receptor, C3aR. Genetic and pharmacological inhibition of C3a/C3aR interaction indicates an important role for C3aR in allergic asthma. C3a/C3aR also enhances the effect of SDF-1 in promoting retention of haematopoietic stem/progenitor cells within the bone marrow.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
C3AR1
Synonyms
C3AR1; complement component 3a receptor 1; C3a anaphylatoxin chemotactic receptor; AZ3B; C3AR; C3a-R; complement component 3 receptor 1; HNFAG09;
Gene ID
MIM
UniProt ID
Q16581
Chromosome Location
12p13.31
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
C3a anaphylatoxin receptor activity; G-protein coupled receptor activity; complement component C3a binding; complement component C3a receptor activity; phosphatidylinositol phospholipase C activity; receptor activity; signal transducer activity;

Quick Inquiry

Please input "biogene" as verification code.

C3AR1 Related Products

Transfected Stable Cell Lines

By Gene symbol(8)
+Expand
By Species(8)
+Expand

Contact Us

USA

Europe

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER