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Human BDKRB2-FLAG Stable Cell Line-HEK293T

Cat.No.
CSC-RG0421
Abbr
HEK293T-HuBDKRB2-FLAG
Alias
BDKRB2,BK 2,B2R,BK2,BK-2,BKR2,BRB2
Growth Properties
Adherent
Host Cell
HEK293T
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
Bradykinin receptor B2 is a G protein-coupled receptor for bradykinin. B2 receptor agonists may have important clinical value in the treatment and prevention of various cardiovascular disorders such as hypertension, ischemic heart disease, left ventricular hypertrophy, ventricular remodeling and congestive heart failure, as well as diabetic disorders by mimicking the reported beneficial effects of bradykinin. Blocking bradykinin B2 receptors after experimental cerebral ischemia reduces brain edema, infarct volume and neuronal necrosis, and improves neurological outcome. Thus, B2 antagonists may be a promising new class of compounds for clinical use after the onset of cerebral ischemia.

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