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Human BDKRB1/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1253
Background
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
BDKRB1
Synonyms
BDKRB1; bradykinin receptor B1; B1 bradykinin receptor; B1BKR; BKR1; bradyb1; BK-1 receptor; bradykinin receptor 1; bradykinin B1 receptor; B1R; BKB1R; BRADYB1;
Gene ID
MIM
UniProt ID
P46663
Chromosome Location
14q32.1-q32.2
Pathway
ACE Inhibitor Pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function
G-protein coupled receptor activity; bradykinin receptor activity; peptide binding; receptor activity; signal transducer activity;

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