Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)
  Email:

Human APLNR Stable Cell Line-CHO-K1/Gα15

Cat.No.
CSC-RG1649
Host Cell
CHO-K1/Gα15
Shipping
Dry Ice
Source
CHO-K1/Gα15
Species
Human
Subgroup
Human
Background
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
Gene Information
Gene Symbol
APLNR
Synonyms
APLNR; apelin receptor; AGTRL1, angiotensin II receptor like 1; APJ; APJ (apelin) receptor; APJR; FLJ90771; APJ receptor; HG11 orphan receptor; angiotensin receptor-like 1; G protein-coupled receptor APJ; G-protein coupled receptor APJ; angiotensin II receptor-like 1; G-protein coupled receptor HG11; HG11; AGTRL1; FLJ96609; MGC45246;
Gene ID
UniProt ID
P35414
mRNA Refseq
BC032688
Chromosome Location
11q12.1
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity;
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
MIM

Quick Inquiry

   Please input "biogene" as verification code.