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Human ADRB2-FLAG Stable Cell Line-CHO

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Cat.No.
CSC-RG0175
Background
Norepinephrine is implicated in a wide range of physiological processes through activation of nine different G-protein-coupled receptors (alpha1a, alpha1b, alpha1d, alpha2a, alpha2b, alpha2c, beta1, beta2, beta3). The human beta2-adrenergic receptor was the first 7-transmembrane receptor for a hormone or neurotransmitter to have its crystal structure solved. It has been suggested that the beta 2-adrenoceptor may form homodimers as well as oligomers with other receptors. The beta 2-adrenoceptor mediates the actions of catecholamines in multiple tissues. They are responsible for relaxation of vascular, uterine, and airway smooth muscle, and are involved in metabolic and endocrine functions.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADRB2
Synonyms
ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR; adrenoceptor beta 2, surface; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptor; adrenergic, beta-2-, receptor, surface
Gene ID
MIM
UniProt ID
P07550
Chromosome Location
5q31-q32
Pathway
Adrenoceptors; Amine ligand-binding receptors; Arf6 signaling events; Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Endocytosis; G alpha (s) signalling events;
Function
adenylate cyclase binding; beta2-adrenergic receptor activity; dopamine binding; drug binding; epinephrine binding; ionotropic glutamate receptor binding; norepinephrine binding; potassium channel regulator activity; protein binding; protein homodimerization activity

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