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Human ADRB1/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1409
Background
Norepinephrine is implicated in a wide range of physiological processes through activation of nine different G-protein-coupled receptors (alpha1a, alpha1b, alpha1d, alpha2a, alpha2b, alpha2c, beta1, beta2, beta3). The human beta1-adrenergic receptor is a 477–amino acid protein found in various heart and brain tissues. beta1 has an important role in the contractile action of valves in cardiac and digestive systems.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADRB1
Synonyms
ADRB1; adrenergic, beta-1-, receptor; ADRB1R; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; RHR; B1AR; BETA1AR;
Gene ID
UniProt ID
P08588
Chromosome Location
10q24-q26
Pathway
Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Function
G-protein coupled receptor activity; PDZ domain binding; alpha-2A adrenergic receptor binding; beta-adrenergic receptor activity; beta1-adrenergic receptor activity; dopamine binding; drug binding; epinephrine binding; norepinephrine binding; protein binding; protein heterodimerization activity; receptor activity; signal transducer activity;

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