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Human ADRB1/Gs Stable Cell Line-CHO

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Cat.No.
CSC-RG0538
Background
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADRB1
Synonyms
ADRB1; adrenergic, beta-1-, receptor; ADRB1R; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; RHR; B1AR; BETA1AR;
Gene ID
UniProt ID
P08588
Chromosome Location
10q24-q26
Pathway
Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Function
G-protein coupled receptor activity; PDZ domain binding; alpha-2A adrenergic receptor binding; beta-adrenergic receptor activity; beta1-adrenergic receptor activity; dopamine binding; drug binding; epinephrine binding; norepinephrine binding; protein binding; protein heterodimerization activity; receptor activity; signal transducer activity;

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