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Human ADRA2B/beta-Arrestin Stable Cell Line-CHO

Cat.No.
CSC-RG1407
Abbr
CHO-HuADRA2B/beta-Arrestin
Alias
ADRA2B,ADRA2L1,ADRA2RL1,ADRARL1,ADRA2L1,ADRA2RL1,ALPHA2BAR
Growth Properties
Adherent
Host Cell
CHO-K1
Morphology
Epithelial-like
Shipping
Dry ice
Species
Human
Background
Adrenergic alpha2b receptor belongs to the group of nine adrenoceptors that mediate the biological actions of the endogenous catecholamines adrenaline and noradrenaline. While alpha2a receptor exerts a tonic sympathoinhibitory function, the alpha2b is responsible for the central hypertensive sympathoexcitatory response. Development of agents capable of selectively activating the alpha2a or blocking the alpha2b may further improve our capability to treat hypertension, ischemic heart disease and heart failure. The alpha2b receptor also contributes to the peripheral regulation of vascular tone.

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