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Human ADRA2A/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1406
Background
Adrenergic alpha2a receptor belongs to the group of nine adrenoceptors that mediate the biological actions of adrenaline and noradrenaline. The alpha2a receptor is expressed in the brain, spleen, kidney, heart and gastrointestinal tract. It is centrally predominant and exerts a tonic sympathoinhibitory function, whereas peripherally it has a vasoconstrictive effect. The alpha2a receptor is also involved in sedation, digestive functions and analgesia.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADRA2A
Synonyms
ADRA2A; ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32; adrenoceptor alpha 2A; alpha-2A adrenergic receptor; alpha-2A adrenoceptor; alpha-2AAR subtype C10; adrenergic, alpha-2A-, receptor; alpha-2 adrenergic receptor subtype C10; alpha-2-adrenergic receptor, platelet type
Gene ID
MIM
UniProt ID
P08913
Chromosome Location
10q25.2
Pathway
Adrenaline signalling through Alpha-2 adrenergic receptor; Adrenoceptors; Amine ligand-binding receptors; Class A/1 (Rhodopsin-like receptors); G alpha (i) signalling events; G alpha (z) signalling events; GPCR downstream signaling;
Function
alpha-1B adrenergic receptor binding; alpha-2C adrenergic receptor binding; alpha2-adrenergic receptor activity; epinephrine binding; heterotrimeric G-protein binding; norepinephrine binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase binding; thioesterase binding

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