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Human ADRA1B/Apoaequorin Stable Cell Line

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Cat.No.
CSC-RG1239
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins. The alpha-adrenergic receptor (AR) subtypes (alpha(1a), alpha(1b), and alpha(1d)) mediate some physiological effects of epinephrine and norepinephrine. The alpha1-AR subtypes are expressed in several organs like brain or heart in which they modulate a diversity of functional effects such as modulation of neurotransmission, vasoconstriction, etc.
Ship
Dry ice
Gene Information
Official Symbol
ADRA1B
Synonyms
ADRA1B; adrenergic, alpha-1B-, receptor; alpha-1B adrenergic receptor; alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; ADRA1; ALPHA1BAR;
Gene ID
MIM
UniProt ID
P35368
Chromosome Location
5q33.3
Pathway
Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem;
Function
G-protein coupled receptor activity; adrenergic receptor activity; alpha1-adrenergic receptor activity; receptor activity; signal transducer activity;

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