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Human ADORA3/Galpha15 Stable Cell Line-Chem-3

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Cat.No.
CSC-RG0603
Background
Extracellular adenosine mediates a multitude of biological effects, including wakefulness, antiarrythmia, bronchoconstriction and response to ischemia and oxidative stress. A family of four GPCR adenosine receptors, A1, A2A, A2B and A3, is responsible for these effects. A3, which couples to Gi/o, is expressed in mast cells along with A2B. Mice lacking A3 display reduced mast cell degranulation and bronchoconstriction in response to adenosine.
Growth Properties
Adherent
Host Cell
Chem-3
Ship
Dry ice
Gene Information
Official Symbol
ADORA3
Synonyms
ADORA3; adenosine A3 receptor; adenosine receptor A3; AD026; A3AR; bA552M11.5; RP11-552M11.7;
Gene ID
MIM
UniProt ID
P33765
Chromosome Location
1p21-p13
Pathway
Adenosine P1 receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
Function
G-protein coupled adenosine receptor activity; receptor activity; signal transducer activity;

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