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Human ADORA2B/Galpha15 Stable Cell Line-Chem-3

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Cat.No.
CSC-RG0602
Background
Extracellular adenosine mediates a multitude of biological effects, including wakefulness, antiarrythmia, bronchoconstriction and response to ischemia and oxidative stress. A family of four G protein-coupled adenosine receptors, A1, A2A, A2B and A3, is responsible for these effects. A2B, which couples to Gs, is expressed in smooth muscle of the bowel, and blood vessels, and mediates relaxation of these tissues in response to adenosine. Airway mast cells also express A2B, which appears to contribute to bronchoconstriction during asthma.
Growth Properties
Adherent
Host Cell
Chem-3
Ship
Dry ice
Gene Information
Official Symbol
ADORA2B
Synonyms
ADORA2B; adenosine A2b receptor; adenosine receptor A2b; ADORA2;
Gene ID
MIM
UniProt ID
P29275
Chromosome Location
17p12
Pathway
Adenosine P1 receptors, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled adenosine receptor activity; receptor activity; signal transducer activity;

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