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Human ADORA2B-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0167
Background
A2B is a receptor for adenosine. A2B receptor is upregulated during intestinal inflammation and mediates key events such as chloride, IL-6 and fibronectin secretion in intestinal epithelial cells. A2B receptor antagonists may have important clinical value in the treatment of inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), as well as inflammatory bowel disease.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
ADORA2B
Synonyms
ADORA2B; adenosine A2b receptor; adenosine receptor A2b; ADORA2;
Gene ID
MIM
UniProt ID
P29275
Chromosome Location
17p12
Pathway
Adenosine P1 receptors, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled adenosine receptor activity; receptor activity; signal transducer activity;

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