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Human ADORA1/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1234
Background
Adenosine is a neuromodulator that is widely distributed in the central and peripheral nervous systems. Many of the actions of adenosine are mediated through G protein-coupled adenosine receptors. Adenosine receptors have been classified into A1, A2A, A2B, and A3 subtypes. Modulation of adenosine receptors by selective agonists and antagonists has potential for the treatment of various cardiovascular inflammatory and neurological diseases.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
ADORA1
Synonyms
ADORA1; adenosine A1 receptor; adenosine receptor A1; RDC7;
Gene ID
MIM
UniProt ID
P30542
Chromosome Location
1q32.1
Pathway
Adenosine P1 receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Morphine addiction, organism-specific biosystem;
Function
G-protein beta/gamma-subunit complex binding; G-protein coupled adenosine receptor activity; G-protein coupled receptor binding; heterotrimeric G-protein binding; phospholipase C activity; protein binding; protein heterodimerization activity; purine nucleoside binding; receptor activity; signal transducer activity;

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