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lgals3

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Official Full Name
lectin, galactoside-binding, soluble, 3
Background
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants
Synonyms
L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS3; Galactose specific lectin 3; L34; L-31; L-34; Laminin binding protein; Lectin L 29; MGC105387; Galectin-3; LGALS2; 35 kDa lectin; IgE-binding protein; MAC-2 antigen; carbohydrate-binding protein 35; galactose-specific lectin 3; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3; galectin 3; MAC 2; lectin; 3 (galectin 3); lectin, galactoside-binding, soluble, 3 (galectin 3)

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