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krt2

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Official Full Name
keratin 2
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Synonyms
K2e; KRTE; CK-2e; KRT2A; KRT2E; MGC116967; MGC116968; KRT2; keratin, type II cytoskeletal 2 epidermal; keratin-2e; keratin-2 epidermis; cytokeratin-2e; type-II keratin Kb2; epithelial keratin-2e; epidermal ichthyosis bullosa of Siemens; keratin 2; keratin 2A (epidermal ichthyosis bullosa of Siemens) , KRT2A; K2e, KRTE, CK-2e, KRT2A, KRT2E

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