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kpna4

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Official Full Name
karyopherin alpha 4 (importin alpha 3)
Background
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Synonyms
KPNA4; karyopherin alpha 4 (importin alpha 3); importin subunit alpha-4; IPOA3; MGC12217; MGC26703; QIP1; SRP3; importin alpha Q1; karyopherin subunit alpha-4; FLJ31113; QIP1, SRP3, IPOA3; impa3; wu:fa56d07; wu:fa66g10; wu:fe14c04; wu:fi04h11; wu:fi19b05; importin subunit alpha-3

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