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klf8

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Official Full Name
Kruppel-like factor 8
Background
This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.
Synonyms
KLF8; Kruppel-like factor 8; Krueppel-like factor 8; BKLF3; DXS741; ZNF741; Basic krueppel-like factor 3; Kruppel like factor 8; MGC138314; Zinc finger protein 741; basic kruppel-like factor 3

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