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kirrel3

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Official Full Name
kin of IRRE like 3 (Drosophila)
Background
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
KIRREL3; kin of IRRE like 3 (Drosophila); kin of IRRE-like protein 3; KIAA1867; KIRRE; NEPH2; Kin of IRRE like 3; Kin of irregular chiasm like protein 3; MRD4; Nephrin like 2; PRO19814; PRO4502; UNQ5923; nephrin-like 2; OTTHUMP00000231130; OTTHUMP00000231131; OTTHUMP00000231132; nephrin-like protein 2; kin of irregular chiasm-like protein 3

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