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kdm4d

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Official Full Name
lysine (K)-specific demethylase 4D
Background
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Synonyms
KDM4D; lysine (K)-specific demethylase 4D; JMJD2D; lysine-specific demethylase 4D; jumonji domain containing 2D; jumonji domain-containing protein 2D; jmjC domain-containing histone demethylation protein 3D

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