The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.
ITGB1BP1; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; bodenin; ICAP 1A; ICAP 1alpha; ICAP 1B; ICAP1; ICAP1A; ICAP1B; integrin cytoplasmic domain associated protein 1; integrin cytoplasmic domain associated protein 1 alpha; integrin cytoplasmic domain associated protein 1 beta; DKFZp686K08158; ICAP 1; ICAP-1; Integrin cytoplasmic domain-associated protein 1; ITBP1_HUMAN; OTTHUMP00000115481; OTTHUMP00000115482; OTTHUMP00000195584; OTTHUMP00000195586; OTTHUMP00000214081; OTTHUMP00000214082; OTTHUMP00000214088; integrin cytoplasmic dom; ICAP-1A; ICAP-1B; ICAP-1alpha; integrin cytoplasmic domain-associated protein 1-beta; integrin cytoplasmic domain-associated protein 1-alpha; zgc:123198; si:dkey-27p7.1