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itga1

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Official Full Name
integrin, alpha 1
Background
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to;form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion;and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor;type I domain which is thought to be involved in collagen binding.
Synonyms
ITGA1; integrin, alpha 1; integrin alpha-1; CD49a; VLA1; VLA-1; laminin and collagen receptor; very late activation protein 1; CD49 antigen-like family member A; alpha1 integrin; alpha 1 integrin

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