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isg15

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Official Full Name
ISG15 ubiquitin-like modifier
Background
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
Synonyms
ISG15; ISG15 ubiquitin-like modifier; G1P2; IP17; UCRP; IFI15; hUCRP; ubiquitin-like protein ISG15; ubiquitin cross-reactive protein; interferon-stimulated protein, 15 kDa; interferon-induced 17-kDa/15-kDa protein; interferon, alpha-inducible protein (clone IFI-15K); G1P2, interferon, alpha inducible protein (clone IFI 15K); interferon-induced 15 kDa protein; interferon-induced 17 kDa protein; si:rp71-1c23.2; zfISG15; interferon stimulated gene, 15 kDa; interferon, alpha-inducible protein

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