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ing1

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Official Full Name
inhibitor of growth family, member 1
Background
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a;nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53;signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple;alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms
ING1; inhibitor of growth family, member 1; inhibitor of growth protein 1; growth inhibitor ING1; growth inhibitory protein ING1; inhibitor of growth 1; p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a; tumor suppressor ING1; zgc:136918

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