This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
HOXB4; homeobox B4; homeo box B4 , HOX2, HOX2F; homeobox protein Hox-B4; Homeo box 2F; Homeo box B4; Homeobox 2F; Homeobox protein Hox B4; Homeobox protein HoxB4; HOX 2; Hox 2.6; Hox 2F; HOX B4; HOX2; Hox2.6; Hox2F; HOXB 4; OTTHUMP00000217026; homeobox protein Hox-2F; homeobox protein Hox-2.6; HOX-2.6; Chox-Z; homeobox protein Hox-Z