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hes7

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Official Full Name
hes family bHLH transcription factor 7
Background
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
HES7; hairy and enhancer of split 7 (Drosophila); transcription factor HES-7; bHLH factor Hes7; bHLHb37; Class B basic helix loop helix protein 37; Class B basic helix-loop-helix protein 37; hairy and enhancer of split 7; HES7_HUMAN; hHes7; Transcription factor HES 7; SCDO4

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