Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


  Order Info:   order info
Products
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

h2-ea-ps

Bookmark and Share
Official Full Name
histocompatibility 2, class II antigen E alpha, pseudogene
Background
This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5 end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype.
Synonyms
H2-EA-PS; histocompatibility 2, class II antigen E alpha, pseudogene; AI323765; E alpha f; H 2 class II histocompatibility antigen E D alpha chain; H 2Ea; H2 class II histocompatibility antigen E D alpha chain; H2 Ea; H2 Ea histocompatibility 2 class II antigen E alpha; H2 IE alpha; H2Ea; Histocompatibility 2 class II antigen E alpha; I E alpha MHC class II; Ia 3; Ia3; Major histocompatibility complex H 2E alpha chain; MGC117888; MHC class II antigen E alpha; Ia-3; H-2Ea; H2-Ea; I-Ealpha; E-alpha-f

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2017 Creative Biogene. All Rights Reserved.
-->