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gstz1

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Official Full Name
glutathione S-transferase zeta 1
Background
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
Synonyms
GSTZ1; glutathione transferase zeta 1; maleylacetoacetate isomerase; GSTZ1 1; MAAI; MAI; EC 2.5.1.18; EC 5.2.1.2; Glutathione S transferase zeta 1; GSTZ1-1; OTTHUMP00000246405; OTTHUMP00000246406; OTTHUMP00000246407; OTTHUMP00000246408; OTTHUMP00000246409; OTTHUMP00000246410; OTTHUMP00000246413; maleylacetone isomerase; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathi; glutathione S-aralkyltransferase; glutathione s-transferase Zeta 1; S-(hydroxyalkyl)glutathione lyase; MGC2029; GSTZ1-1, MAAI, MAI, MGC2029, GSTZ1; glutathione transferase zeta 1 (maleylacetoacetate isomerase); zgc:92869; zgc:113898

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