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gpbp1

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Official Full Name
GC-rich promoter binding protein 1
Background
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms
GPBP1; GC-rich promoter binding protein 1; vasculin; DKFZp761C169; GC rich promoter binding protein 1; GPBP; MGC126339; Vascular wall linked; vascular wall-linked protein; SSH6

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