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gmnn

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Official Full Name
geminin, DNA replication inhibitor
Background
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
Synonyms
GMNN; geminin, DNA replication inhibitor; geminin; Gem; sb:cb254; zgc:66217

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