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glce

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Official Full Name
glucuronic acid epimerase
Background
Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of;circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic;acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines;(Ghiselli and Agrawal, 2005 (PubMed 15853773)).
Synonyms
GLCE; glucuronic acid epimerase; D glucuronyl C5 epimerase , UDP glucuronic acid epimerase; D-glucuronyl C5-epimerase; heparan sulfate epimerase; HSEPI; KIAA0836; D glucuronyl C5 epimerase; Heparin/heparan sulfate:glucuronic acid C5 epimerase; glucuronyl C5-epimerase; UDP-glucuronic acid epimerase; heparin/heparan sulfate-glucuronic acid C5-epimerase; heparin/heparan sulfate:glucuronic acid C5-epimerase

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