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gja8

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Official Full Name
gap junction protein, alpha 8, 50kDa
Background
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
Synonyms
GJA8; gap junction protein, alpha 8, 50kDa; CAE, CAE1, CZP1, gap junction protein, alpha 8, 50kD (connexin 50) , gap junction protein, alpha 8, 50kDa (connexin 50); gap junction alpha-8 protein; connexin 50; CX50; connexin-50; lens fiber protein MP70; c; Cx45.6; connexin 45.6; connexin-45.6

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