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gins4

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Official Full Name
GINS complex subunit 4 (Sld5 homolog)
Background
SLD5 or GINS4 is a member of the GINS complex which is involved in initiation of replication and unwinding of DNA. It is highly conserved amongst eukaryotes. The GINS complex in yeast associates with DNA polymerase epsilon and stimulates its catalytic activity. It also interacts with Cdc45 and the MCM2-7 complex to activate the eukaryotic minichromosome maintenance helicase.
Synonyms
GINS complex subunit 4; GINS4; SLD5 homolog; SLD5; MGC14799; GINS complex subunit 4 (Sld5 homolog); 2810037C03Rik; 4933405K01Rik; DNA replication complex GINS protein SLD5; im:7137690; zgc:100817

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