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gga1

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Official Full Name
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Background
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
GGA1; ADP-ribosylation factor binding protein; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; fb33h10; im:6912200; wu:fb33h10; zgc:101044; ADP-ribosylation factor-binding protein GGA1; golgi associated, gamma adaptin ear containing, ARF binding protein 1

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