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gclm

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Official Full Name
glutamate-cysteine ligase, modifier subunit
Background
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Synonyms
GCLM; glutamate-cysteine ligase, modifier subunit; GLCLR; glutamate--cysteine ligase regulatory subunit; gamma glutamylcysteine synthetase; Gamma ECS regulatory subunit; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; Glutamate cysteine ligase regulatory subunit; Glutamate--cysteine ligase modifier subunit; GSH0_HUMAN; GSC light chain; OTTHUMP00000012299; glutamate-cysteine ligase regulatory protein; gamma-glutamylcysteine synthetase regula; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); zgc:55903; id:ibd3182; wu:fi24c07

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