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gckr

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Official Full Name
glucokinase (hexokinase 4) regulator
Background
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]
Synonyms
GCKR; glucokinase (hexokinase 4) regulator; GKRP; FGQTL5; glucokinase regulatory protein; glucokinase (hexokinase 4) regulatory protein; GKRP, FGQTL5

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