Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


  Order Info:   order info
Products
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

galectin-3

Bookmark and Share
Official Full Name
Galectin-3
Background
Galectin-3 is a galactose-specific lectin which binds IgE. This lectin may mediate with the alpha-3, beta-1 integrin for the stimulation by CSPG4 of endothelial cells migration. Found together with DMBT1, which is required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus, it acts as a pre-mRNA splicing factor. Galectin-3 is involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. It probably forms homo- or heterodimers. Additionally, galectin-3 interacts with DMBT1. This lectin forms a complex with ITGA3, ITGB1 and CSPG4. It also interacts with LGALS3BP, LYPD3, CYHR1 and UACA. It is highly expressed in the colonic epithelium and abundant in activated macrophages.
Synonyms
LGALS3; CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2; 35 kDa lectin; IgE-binding protein; MAC-2 antigen; carbohydrate-binding protein 35; galactose-specific lectin 3; laminin-binding protein; lectin L-29

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2017 Creative Biogene. All Rights Reserved.
-->