The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene.
FRMD3; FERM domain containing 3; FERM domain-containing protein 3; EPB41L4O; MGC20553; 4.1O; Band 4.1 like protein 4O; FERM domain containing protein 3; Ovary type protein 4.1; P410; protein 4.1O; band 4.1-like protein 4; band 4.1-like protein 4O; EPB41LO; RP11-439K3.2; 4.1O, P410, EPB41LO, EPB41L4O, RP11-439K3.2