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frat1

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Official Full Name
frequently rearranged in advanced T-cell lymphomas
Background
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
Synonyms
FRAT1; frequently rearranged in advanced T-cell lymphomas; proto-oncogene FRAT1; FRAT-1; frequently rearranged in advanced T-cell lymphomas 1; FLJ97193

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