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fkbp3

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Official Full Name
FK506 binding protein 3, 25kDa
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Synonyms
FKBP3; FK506 binding protein 3, 25kDa; FK506 binding protein 3 (25kD); peptidyl-prolyl cis-trans isomerase FKBP3; FKBP 25; PPIase; FKBP 3; FKBP25; Rotamase; 25 kDa FKBP; PPIase FKBP3; OTTHUMP00000178918; immunophilin FKBP25; rapamycin binding protein; 25 kDa FK506-binding protein; FK506-binding protein 3 (25kD); FK506-binding protein 25, T-cell; rapamycin-selective 2; FKBP-3; FKBP-25; rapamycin-selective 25 kDa immunophilin; putative FK506-binding protein; FK506 binding protein 3; FK506; fb75c04; wu:fb75c04; zgc:110728; si:dz261o22.2

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